Manchester United and England captain Wayne Rooney is facing about six weeks on the sidelines with a knee injury.
Rooney picked up the injury in last weekend’s loss at Sunderland and could now miss United’s next eight matches.
“He scores a lot of goals so he is very important for us. We know that but we have to cope,” said manager Louis van Gaal.
The 30-year-old forward has not been included in the squad for Thursday’s Europa League match at FC Midtjylland.