Manchester United manager Jose Mourinho said on Monday he did not know whether midfielder Paul Pogba would return for Tuesday’s Champions League last-16 second-leg tie against Sevilla.
Pogba has returned to training after missing Saturday’s 2-1 Premier League victory over Liverpool.
Forward Anthony Martial could return at Old Trafford after missing two matches.
The first leg in Seville finished 0-0 thanks largely to a superb first-half save from United’s David de Gea.
The Red Devils will be without defenders Phil Jones, Marcos Rojo and Daley Blind, and midfielder Ander Herrera.
And Tuesday’s game could come too soon for striker Zlatan Ibrahimovic, who is regaining fitness after almost three months out with a knee injury.
Midfielder Michael Carrick will hope to be included after confirming on Monday that he will retire at the end of the season.
Sevilla will be without defender Sebastien Corchia, while Daniel Carrico is also a doubt.
Former Manchester City winger Jesus Navas is unlikely to make the squad as he recovers from injury.
The Spanish side had the better of the first leg, but a combination of De Gea’s saves and poor finishing left them frustrated.
United, who were playing their first Champions League knockout game in four years, have won 15 of their 18 home games so far this season.
“I think it is a very difficult match,” said Mourinho. “We are going to try to prove that we are better [than the first leg].”