Bottom club Aston Villa were well beaten by Everton as home supporters walked out in protest at American owner Randy Lerner.
Fans headed for the exits in the 74th minute – Villa were formed in 1874 – with their side trailing 3-0.
Ramiro Funes Mori gave Everton the lead by meeting Kevin Mirallas’ corner before Aaron Lennon’s close-range finish doubled their lead.
Romelu Lukaku made it 3-0 before Rudy Gestede headed a consolation for Villa.
The result leaves the home side eight points from safety with 10 games left.
Fans vent their anger at Lerner
Mathematically, Villa can still avoid a first relegation since 1987.
Yet with five of their remaining 10 games against Manchester City (away), Tottenham (home), Chelsea (home), Manchester United (away) and Arsenal (away), they have their work cut out to avoid the drop.