ohn Thomas McNamara, a father-of-three, was a leading amateur rider before being seriously injured.
He fractured two vertebrae in his neck after being thrown from his horse Galaxy Rock in the Fulke Walwyn Kim Muir Challenge Cup on 14 March, 2013.
He moved back home to Limerick in 2014 after being discharged from the North West Regional Spinal Injuries Centre.
Adrian McGoldrick, senior medical officer for the Irish Turf Club confirmed McNamara “passed away peacefully during the night”.
McNamara rode four winners at the Cheltenham Festival, including guiding Teaforthree to victory in the 2012 National Hunt Chase.
He won the same race in 2002 on Rith Dubh, was successful in the Cross-Country Chase with Spot Thedifference three years later and won the 2007 Fox Hunter Chase on Drombeag.
A minute’s silence will be held at the Galway Festival on Tuesday as a mark of respect, before the second race at 17:45 BST.